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Знакомьтесь! Хеликобактер пилори!

07.07.2011 11:55 Рейтинг: 4

С недавнего времени язва желудка и двенадцатиперстной кишки не считается таким уж страшным заболеванием. А помните, когда-то слово “язвенник” означало чуть ли не инвалид! Если нашли язву, операции не избежать, отрежут половину желудка. А потом всю жизнь на диете, ничего нельзя, напрягаться нельзя и ни грамма алкоголя!И вот постепенно положение язвенников начало улучшаться. Все чаще и чаще из кабинета гастроэнтеролога пациенты стали выходить не с направлениями в больницу, а с назначением курса антибиотиков. Порой доходило до казусов. Люди не понимали - как же так, у меня язва! Причем здесь антибиотики! Врач-неуч! Коновал! Залечить хочет!Однако, врач всё прописал правильно. Оказывается, все дело в особой бактерии, живущей в желудке. Название её Хеликобактер пилори (Helicobacter pylori), что отражает место её обитания - “пилори”, т.е пилорический отдел желудка, а также форму самой бактерии “хелико”, т.е. спиралевидный, винтообразный.Было установлено, что бактерия может выживать в кислой среде желудка, что ранее считалось невозможным, а также отмечен тот факт, что бактерию находят в основном у пациентов с гастритом и язвенной болезнью. Тогда-то и зародилась у ученых мысль, что эта бактерия является причиной большинства заболеваний желудка. Прием антибиотиков в составе терапии может существенно помочь выздоровлению больного.Авторы этого открытия доктор Барри Маршал и Робин Уоррен получили нобелевскую премию в области медицины в 2005 году.Хеликобактер пилори была тщательно исследована и, надо сказать, немало удивила ученых. Прежде всего их интересовало - а как же бактерия способна противостоять кислой среде желудка, ведь там ничего живое выжить не может? Оказывается, она содержит фермент уреазу, которая расщепляет мочевину с образованием аммиака. Аммиак нейтрализует соляную кислоту желудка и обеспечивает бактерии комфортный защитный слой. Кроме того, у бактерии имеются жгутики, благодаря которым она быстро плавает даже в вязкой среде и быстро внедряется в слой слизи, покрывающей стенки желудка и защищающей их от воздействия кислоты. Что же происходит дальше? А дальше своими спиралевидными жгутиками бактерия просверливает вход в слизистую оболочку желудка и пристраивается в клетки эпителия. Там она надежно защищена от кислоты. Хеликобактер пилори питается клетками эпителия и выделяет токсические продукты обмена веществ, вызывая воспаление и разрушение клеток. Поскольку клетки теперь не защищены от соляной кислоты, на этом месте постепенно образуется язва. Существует несколько разновидностей (штаммов) этой бактерии. Различаются они степенью патогенности для человека, т.е. масштабами разрушений, которые они могут устроить в желудке. Причем, выяснилось, что у абсолютно здорового человека может развиться гастрит, а потом и язвенная  болезнь (если он заразился особенно злым штаммом), и при соблюдении диеты, в отсутствие всяких стрессов, иными словами - настоящая инфекция! Сейчас доказана и роль Хеликобактер пилори в возникновении опухолевых процессов. Однако, почему же никто не бьет тревогу? Наоборот, среди врачей-гастроэнтерологов царит, казалось бы, безмятежное спокойствие. На то есть две причины. Во-первых зловредная бактерии прекрасно поддается лечению антибиотиками. А во-вторых, после проведения масштабных исследований, выяснилось, что в России количество носителей Helicobacter pylori достигает 70 % населения и подавляющее большинство из них не страдает какими-либо заболеваниями желудочно-кишечного тракта. Предполагается, что при нормальном функционировании иммунной системы, а также, если заражение произошло не очень патогенным штаммом, организм в состоянии справиться с бактерией самостоятельно. Болезнь не возникает, хотя Хеликобактер пилори и обнаруживается в желудке. Просто концентрация их слишком мала, иммунная система вырабатывает достаточно антител, чтобы сдерживать рост микроорганизмов. И вот здесь поговорка “все болезни от нервов” оказывается как нельзя более правдоподобной. Не так опасен короткий и мощный стресс, как тихий и постоянный. Как правило, это стресс бытовой, конфликтная ситуация на работе, в семье. В этом случае надпочечники начинают вырабатывать гормоны - кортикостероиды, практически не останавливаясь. А кортикостероиды обладают свойством подавлять активность иммунной системы и она уже не может сдержать рост патогенных микробов,  в том числе и Хеликобактер пилори. Размножаясь в желудке, бактерия вызывает гастрит, а потом и язву. Поэтому очень важно иметь здоровую иммунную систему и крепкие нервы. Хороший совет, но выполним он лишь частично. Современная жизнь готовит нам стрессы на каждом шагу. Просьбы перестать нервничать зачастую кажутся просто смешными. Поэтому нужно сделать упор на здоровый иммунитет. Хотя и для тех, кто не может похвастаться сильным иммунитетом есть хорошие новости. Научное сообщество рапортует о начале исследований в области разработки вакцины против язвы. Ведь наш организм способен вырабатывать антитела на любые бактерии, значит и на Хеликобактер тоже. Но, пока эти исследования только начались, можно заняться укреплением иммунитета с помощью фитотерапии. Отличный вариант - полисахариды древесного гриба Шиитаке, это не просто иммуностимулятор, это вещество природного происхождения, которое корректирует работу слабых звеньев иммунной системы и сдерживает активность чересчур сильных. Тогда и гастрит не страшен и язва!

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